Treatment depends on severity. Mild to moderate arthrosis can be treated with cartilage protectors (glucosamine and chondroitin) and physiotherapy. Viscosupplementation (infiltration with hyaluronic acid) or infiltrations with growth factors can be a useful tool in the management of these cases. In cases where there is associated deformity, surgical correction can interrupt or delay, and in some cases even reverse, the arthrosis process in progress. In severe cases, arthroplasty (prosthesis) is the most consensual solution with the most predictable results, and is the only option that provides long-term relief from complaints. The knee joint is divided into three compartments. The inner (medial) compartment, the outer (lateral) compartment and the kneecap. Depending on the extent of the arthrosis, we can opt for a total prosthesis or a prosthesis that replaces only the affected compartment. In the unicompartmental prosthesis, only the affected compartment is replaced, maintaining all the original biomechanics of the knee, which gives a more natural sensation after surgery and a faster, less painful faster and less painful recovery. In cases where the wear and tear has already extended to several compartments of the knee, it is a total prosthesis is required.